Demystifying the Hill Equation for Assay Developers
The Hill-model and similar ones are often used in the fields of drug discovery to model experimental data from dose-response-, binding- or bioassays. In this blog post I will try…
Spearman-Kärber analysis and the Creutzfeld-Jakob disease
A non-parametric analysis to determine the ED50, SD50 or similar metrics The first time I came across the term Spearman-Kärber was with the analysis of RT-QuIC. These assays are typically…